Original paper
Establishment of a Bernard-Soulier syndrome model in zebrafish
Abstract
Platelets play an essential role in thrombosis and hemostasis. Abnormal hemostasis can cause spontaneous or severe post-traumatic bleeding. Bernard-Soulier syndrome (BSS) is a rare inherited bleeding disorder caused by a complete quantitative deficiency in the GPIb-IX-V complex. Multiple mutations in GP9 lead to the clinical manifestations of BSS. Understanding the roles and underlying mechanisms of GP9 in thrombopoiesis and establishing a...
Paper Details
Title
Establishment of a Bernard-Soulier syndrome model in zebrafish
Published Date
Aug 19, 2021
Journal
Volume
107
Issue
7
Pages
1655 - 1668
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Notes
History