Riyang Zhou
South China University of Technology
Publications 1
#1Qing Lin (SCUT: South China University of Technology)
#2Riyang Zhou (SCUT: South China University of Technology)
Last. Yiyue Zhang (SCUT: South China University of Technology)H-Index: 19
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Platelets play an essential role in thrombosis and hemostasis. Abnormal hemostasis can cause spontaneous or severe post-traumatic bleeding. Bernard-Soulier syndrome (BSS) is a rare inherited bleeding disorder caused by a complete quantitative deficiency in the GPIb-IX-V complex. Multiple mutations in GP9 lead to the clinical manifestation of BSS. Understanding the roles and underlying mechanisms of GP9 in thrombopoiesis and establishing a proper animal model of BSS would be valuable to understan...