Haematologica
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#1Haesook T. Kim (Harvard University)H-Index: 74
#2Peter Baker (Harvard University)
Last. Rizwan Romee (Harvard University)H-Index: 24
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#1Philip Young-Ill Choi (Canberra Hospital)
#2Danny Hsu (Liverpool Hospital)H-Index: 2
Last. Robert Bird (Princess Alexandra Hospital)H-Index: 16
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#1Lale Kostakoglu (UVA: University of Virginia)H-Index: 3
#2Federico Mattiello (Hoffmann-La Roche)H-Index: 5
Last. Antonio PintoH-Index: 51
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This retrospective analysis of the phase III GOYA study investigated the prognostic value of baseline metabolic tumor volume parameters and maximum standardized uptake values for overall and progression-free survival in treatment-naive diffuse large B-cell lymphoma. Baseline total metabolic tumor volume (determined for tumors >1 mL using a threshold of 1.5 times the mean liver standardized uptake value +2 standard deviations), total lesion glycolysis, and maximum standardized uptake value positr...
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#1Samer A. Srour (University of Texas MD Anderson Cancer Center)H-Index: 9
#2Denái R. Milton (University of Texas MD Anderson Cancer Center)H-Index: 23
Last. Ruby Delgado (University of Texas MD Anderson Cancer Center)H-Index: 7
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#1Paolo Gresele (University of Perugia)H-Index: 69
#2Stefania Momi (University of Perugia)H-Index: 29
Last. Armando Tripodi (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)H-Index: 28
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The Covid-19 pandemic has heavily impacted global health and economy and vaccination remains the primary way of controlling the infection. During the ongoing vaccination campaign some unexpected thrombotic events have emerged in subjects who recently received the AstraZeneca Vaxzevria vaccine or the Johnson and Johnson (Janssen) vaccine, two adenovirus vector-based vaccines. Epidemiological studies confirm that the observed/expected rate of these unusual thromboses is abnormally increased, espec...
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#1Qing Lin (SCUT: South China University of Technology)
#2Riyang Zhou (SCUT: South China University of Technology)
Last. Yiyue Zhang (SCUT: South China University of Technology)H-Index: 19
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Platelets play an essential role in thrombosis and hemostasis. Abnormal hemostasis can cause spontaneous or severe post-traumatic bleeding. Bernard-Soulier syndrome (BSS) is a rare inherited bleeding disorder caused by a complete quantitative deficiency in the GPIb-IX-V complex. Multiple mutations in GP9 lead to the clinical manifestation of BSS. Understanding the roles and underlying mechanisms of GP9 in thrombopoiesis and establishing a proper animal model of BSS would be valuable to understan...
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#1Loredana Bury (University of Perugia)H-Index: 16
#2Emanuela Falcinelli (University of Perugia)H-Index: 24
Last. Paolo Gresele (University of Perugia)H-Index: 69
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Platelet-type von Willebrand disease (PT-VWD) is an inherited platelet disorder characterized by macrothrombocytopenia and mucocutaneous bleeding, of variable severity, due to gain-of-function variants of GP1BA conferring to glycoprotein Ibα (GPIbα) enhanced affinity for von Willebrand factor (VWF). The bleeding tendency is conventionally attributed to thrombocytopenia and large VWF-multimers depletion. Some clues, however, suggest that platelet dysfunction may contribute to the bleeding phenoty...
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#1Eileen Haring (DKFZ: German Cancer Research Center)
#2Geoffroy Andrieux (DKFZ: German Cancer Research Center)H-Index: 9
Last. Annette Schmitt-Graeff (University of Freiburg)H-Index: 48
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Acute graft-versus-host disease (GVHD) is a life-threatening complication of allogeneic hematopoietic cell transplantation (allo-HCT), a potentially curative treatment for leukemia. Endoplasmic reticulum (ER) stress occurs when the protein folding capacity of the ER is oversaturated. How ER stress modulates tissue homeostasis in the context of alloimmunity is not well understood. We show that ER stress contributes to intestinal tissue injury during GVHD and can be targeted pharmacologically. We ...
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#1Elia Colin (University of Paris)
#2G. Courtois (University of Paris)
Last. Lydie Da Costa (University of Paris)H-Index: 16
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#1Dietger Niederwieser (Lithuanian University of Health Sciences)
#2Helen Baldomero (University Hospital of Basel)H-Index: 42
Last. Nada Hamad (St. Vincent's Health System)H-Index: 9
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The Worldwide Network of Blood and Marrow Transplantation (WBMT) pursues the mission of promoting hematopoietic cell transplantation (HCT) for instance by evaluating activities through member societies, national registries and individual centers. In 2016, 82,718 first HCTs were reported from 1662 HCT teams in 86 of the 195 World Health Organization member states representing a global increase of 6.2% in autologous and 7.0% in allogeneic HCT and bringing the total to 1,298,897 procedures. Assumin...
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Top fields of study
Immunology
Leukemia
Myeloid leukemia
Bone marrow
Cancer research
Diabetes mellitus
Medicine
Biology