Original paper
P2-140: Convergent Evidence of Pupillary Response as an Early Indicator of Locus Coeruleus Dysfunction and Risk for MCI
Abstract
There is a great need for early screening tools of Alzheimer’s disease (AD) as pathology may be present decades before symptom onset. Task-evoked pupil dilation (TEPD) is a well-validated measure of mental effort which may detect subtle declines in cognitive efficiency prior to impaired performance. During a digit span task, TEPD increases with cognitive load but decreases after capacity is exceeded. TEPD is also linked to functioning of the...
Paper Details
Title
P2-140: Convergent Evidence of Pupillary Response as an Early Indicator of Locus Coeruleus Dysfunction and Risk for MCI
Published Date
Jul 1, 2016
Journal
Volume
12
Issue
7S_Part_13
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Notes
History