Greater cortical thinning in normal older adults predicts later cognitive impairment
Abstract
Cross-sectional studies have shown regional differences in cortical thickness between healthy older adults and patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI). We now demonstrate that participants who subsequently develop cognitive impairment leading to a diagnosis of MCI or AD (n = 25) experience greater cortical thinning in specific neuroanatomic regions compared with control participants who remained cognitively...
Paper Details
Title
Greater cortical thinning in normal older adults predicts later cognitive impairment
Published Date
Feb 1, 2015
Journal
Volume
36
Issue
2
Pages
903 - 908
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