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Review paper

Association of proton‐pump inhibitor use with adverse health outcomes: A systematic umbrella review of meta‐analyses of cohort studies and randomised controlled trials

Volume: 88, Issue: 4, Pages: 1551 - 1566
Published: Oct 9, 2021
Abstract
Aims The aim was to perform an umbrella review to summarise the existing evidence on proton‐pump inhibitor (PPI) use and adverse outcomes and to grade the certainty of evidence. Methods Electronic databases were searched up to July 2021 for meta‐analyses of cohort studies and/or randomised controlled trials (RCTs). Summary effect sizes from a random‐effects model, between‐study heterogeneity, 95% prediction interval, small‐study effect, excess...
Paper Details
Title
Association of proton‐pump inhibitor use with adverse health outcomes: A systematic umbrella review of meta‐analyses of cohort studies and randomised controlled trials
Published Date
Oct 9, 2021
Volume
88
Issue
4
Pages
1551 - 1566
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