Refractory Chylothorax and Lymphedema Caused by Advanced Gastric Cancer

Published on Nov 1, 2019in Internal Medicine1.005
· DOI :10.2169/INTERNALMEDICINE.2351-18
Naoko Nagano3
Estimated H-index: 3
,
Manabu Suzuki5
Estimated H-index: 5
+ 7 AuthorsHaruhito Sugiyama19
Estimated H-index: 19
Sources
Abstract
: Chylothorax is the accumulation of lipid pleural effusion. Few reports have described chylothorax caused by gastric cancer. A 45-year-old woman presented with progressive lymphedema and bilateral chylothorax. Although repetitive thoracentesis was performed to relieve her dyspnea, swelling of her axillary lymph nodes became significant. Positron emission tomography/computed tomography demonstrated the accumulation of 18F-fluorodeoxyglucose in these nodes, and a lymph node biopsy showed signet ring cell carcinoma. The primary site was a 0-IIc type lesion in the gastric body that was only detected by upper gastrointestinal endoscopy. The patient was diagnosed with advanced gastric cancer 3.5 months after presentation for chylothorax.
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15 CitationsSource
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Chylothorax is the accumulation of lymph fluid in the pleura. Gastric carcinoma with chylothorax and lymphedema as the initial manifestations has rarely been reported, with only 14 cases reported to date. The mechanisms of gastric carcinoma generating chylothorax have not yet been determined. The current study reports the case of a 63-year-old woman presenting with chylothorax and lower extremity lymphedema, and reviews the existing literature. A chest radiograph performed on the present patient...
4 CitationsSource
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Lymphedema is a chronic, progressive, and often debilitating condition. Primary lymphedema is a lymphatic malformation developing during the later stage of lymphangiogenesis. Secondary lymphedema is the result of obstruction or disruption of the lymphatic system, which can occur as a consequence of tumors, surgery, trauma, infection, inflammation, and radiation therapy. In this review, we report an update upon the diagnostic approach and the medical and surgical therapy for both primary and seco...
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The patient, a 77 year-old woman, visited our hospital with chief complaints of coughing and dyspnea. Chest radiography revealed bilateral pleural effusion especially on the right side, and she was admitted to our hospital to undergo a more thorough examination. The pleural effusion was identified as chyle. In cytodiagonosis, a number of adenocarcinoma cells in clumps were detected. After admission, her general condition worsened, and she died. Her condition was diagnosed as advanced gastric car...
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7 CitationsSource
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