Immunofluorescence Study of Ocular Mucin 5AC Expression 28 Days Post Sulfur Mustard Exposure

Ocular sulfur mustard (SM) injuries can lead to the sloughing off of corneal epithelial cells by the formation and fusion of microbullae. Previous ex vivo work has shown that activation of MMP9 and ADAM17 lead to this sloughing. This type of injury also occurs in Dry Eye Syndrome (DES). By treating vesicant exposed eyes with a FDA approved drug for DES (Restasis) the integrity of the corneal epithelium to the underlying stroma can be...