Peihong Zhou
Rutgers University
Messenger RNAAnatomyPathologyMolecular biologyAndrologyTumor necrosis factor alphaChemistryImmunologyCorneaImmunofluorescenceNitrogen mustardUmbilical arterySulfur mustardCollagen, type I, alpha 1SubfamilyEpitheliumMedicineBiologyCell biology
33Publications
9H-index
680Citations
Publications 24
Newest
#1Laurie B. Joseph (RU: Rutgers University)H-Index: 12
#2Marion K. Gordon (RU: Rutgers University)H-Index: 21
Last. Jeffrey D. Laskin (RU: Rutgers University)H-Index: 69
view all 8 authors...
Sulfur mustard (SM; bis (2-chloroethyl) sulfide) is a potent vesicant which causes irritation of the conjunctiva and damage to the cornea. In the present studies, we characterized the ocular effects of SM in New Zealand white rabbits. Within one day of exposure to SM, edema and hazing of the cornea were observed, followed by neovascularization which persisted for at least 28 days. This was associated with upper and lower eyelid edema and conjunctival inflammation. The conjunctiva is composed of ...
Source
Source
#1Andrea DeSantis-Rodrigues (RU: Rutgers University)H-Index: 2
#2Rita A. Hahn (RU: Rutgers University)H-Index: 8
Last. Marion K. Gordon (RU: Rutgers University)H-Index: 21
view all 8 authors...
Amino-Plex (SM1997) is a spray or liquid cosmeceutical that has been used for skin dryness, aging, or sun exposure. Its formulation includes electrolytes, trace minerals, amino acids, peptides, nucleosides and nucleotides, all substances that are less than 10 kDa. It is designed to increase oxygen levels in cells, improve glucose transport, stimulate ATP synthesis, and stimulate collagen formation, actions that can help facilitate repair of damaged cells. It also supports collagen synthesis and ...
Source
#1Yoke Chen Chang (RU: Rutgers University)H-Index: 3
#2James D. Wang (RU: Rutgers University)H-Index: 2
Last. Donald R. Gerecke (RU: Rutgers University)H-Index: 18
view all 8 authors...
: Laminin-332 is a basement membrane protein composed of three genetically distinct polypeptide chains that actively promote both skin epidermal cell adhesion and migration. Proteolytic fragments of the laminin γ2 chain stimulate migration and scattering of keratinocytes and cancer cells. Sulfur mustard (SM) is a bifunctional alkylating agent that induces separation of basal keratinocytes from the dermal-epidermal junction and invokes a strong inflammatory response leading to delayed wound repai...
1 CitationsSource
#1Marion K. Gordon (RU: Rutgers University)H-Index: 21
#2Donald R. Gerecke (RU: Rutgers University)H-Index: 18
Last. Yoke-Chen Chang (RU: Rutgers University)H-Index: 7
view all 6 authors...
1 CitationsSource
#1Marion K. Gordon (RU: Rutgers University)H-Index: 21
#2Rita Hahn (RU: Rutgers University)H-Index: 3
Last. Donald R. Gerecke (RU: Rutgers University)H-Index: 18
view all 5 authors...
Purpose: Organ cultures of rabbit corneas have been used to ascertain the effectiveness of a human fibroblast growth factor (FGF)-1 derivative (TTHX1114), lacking cysteine residues, to protect against and/or repair epithelial lesions following exposure to nitrogen mustard (NM). Methods: Rabbit corneas were exposed to NM and cultured for up to 14 days, with or without drug (TTHX1114). At specified times, tissue was examined by histopathology and graded by a novel composite scale. Proliferation wa...
4 CitationsSource
#1Marion K. Gordon (RU: Rutgers University)H-Index: 21
#2Rita A. A. Hahn (RU: Rutgers University)
Last. Peihong Zhou (RU: Rutgers University)H-Index: 9
view all 3 authors...
#1Marion K. Gordon (RU: Rutgers University)H-Index: 21
#2Rita A. Hahn (RU: Rutgers University)H-Index: 8
Last. Donald R. Gerecke (RU: Rutgers University)H-Index: 18
view all 6 authors...
#1Marion K. Gordon (RU: Rutgers University)H-Index: 21
#2Andrea DeSantis-Rodrigues (RU: Rutgers University)H-Index: 2
Last. Donald R. Gerecke (RU: Rutgers University)H-Index: 18
view all 8 authors...
1 Citations