Dementia and epilepsy

It is not news that people with dementia, including Alzheimer disease (AD), the most frequently identified cause of dementia, are at increased risk to develop epilepsy.1 There has been increased interest in this association because of studies demonstrating accumulation of β -amyloid (Aβ) peptide in animal models of AD leading to recurrent seizure activity.2 These seizures, and in turn the physiologic response to seizures, contribute to...