Neurology
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#2Roxana AmeliH-Index: 3
Last. Romain Marignier (INSERM: Inserm)H-Index: 31
view all 47 authors...
Objectives: null To report the clinical, biological, imaging features, and the clinical course of a French cohort of patients with glial fibrillar acidic protein (GFAP) autoantibodies. null Methods: null We retrospectively included all patients tested positive for GFAP antibodies in the cerebrospinal fluid, by immunohistochemistry and confirmed by cell-based assay using cells expressing human GFAPα, since 2017, from two French referral centers. null Results: null We identified 46 patients with G...
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#1Philipp Karschnia (Yale University)H-Index: 8
#2Leon D. Kaulen (Yale University)H-Index: 6
Last. Joachim M. Baehring (Yale University)H-Index: 29
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A 64-year-old man presented for evaluation of proximally pronounced weakness of the arms with preserved facial and lower extremity strength. Symptoms slowly developed over the last two years, and the patient's history was notable for severe Listeria monocytogenes meningitis four years prior to presentation, which was adequately treated with antibiotics. On examination, symptoms clinically reassembled 'man-in-the-barrel' syndrome and localized to the cervicothoracic central cord. Blood analysis w...
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#1Guillermo Delgado-García (UoC: University of Calgary)H-Index: 7
#2Birgit Frauscher (MNI: Montreal Neurological Institute and Hospital)H-Index: 60
Stereo-electroencephalography (SEEG) is not only a sophisticated and highly technological investigation but a new and better way to conceptualize the spatial and temporal dynamics of epileptic activity. The first intracranial investigations with SEEG were carried out in France in the mid-twentieth century; however, its use in North America is much more recent. Given its significantly lower risk of complications and its ability to sample both superficial and deep structures as well as both hemisp...
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#1Albert M. Isaacs (WUSTL: Washington University in St. Louis)H-Index: 9
#2Jeffrey J. Neil (WUSTL: Washington University in St. Louis)H-Index: 68
Last. Christopher D. SmyserH-Index: 27
view all 17 authors...
Background and Objectives: null The neurological deficits of neonatal post-hemorrhagic hydrocephalus (PHH) have been linked to periventricular white matter injury. To improve understanding of PHH-related injury, diffusion basis spectrum imaging (DBSI) was applied in neonates, modeling axonal and myelin integrity, fiber density, and extra-fiber pathologies. Objectives included characterizing DBSI measures in periventricular tracts, associating measures with ventricular size, and examining MRI fin...
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#1Samir Alkabie (BCM: Baylor College of Medicine)
#2Omar Tanweer (BCM: Baylor College of Medicine)
Last. Fernando X. Cuascut (BCM: Baylor College of Medicine)H-Index: 6
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We present the case of a 57-year-old man with protein S deficiency and left leg deep vein thrombosis (DVT) five years prior, who developed stepwise progressive bilateral lower limb weakness, numbness/paresthesia, gait imbalance, hesitancy of micturition, and constipation in the setting of recurrent left common femoral DVT treated with apixaban. Symptoms amplified with Valsalva, corticosteroids, and post-lumbar puncture, with longitudinally extensive mid-thoracic T2-hyperintense lesion extending ...
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#1Haruo Nishijima (Hirosaki University)H-Index: 12
#2Tomoya Kon (Hirosaki University)H-Index: 12
Last. Masahiko Tomiyama (Hirosaki University)H-Index: 21
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#1Andrew McKeon (Mayo Clinic)H-Index: 66
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#1Blake H Fortes (Mayo Clinic)H-Index: 3
#2John J. Chen (Mayo Clinic)H-Index: 22
Last. M. Tariq Bhatti (Mayo Clinic)H-Index: 9
view all 3 authors...
A 31-year-old healthy white male experienced painless sequential vision loss. Brain imaging and laboratory investigations for infectious, inflammatory, and nutritional conditions, in addition to targeted genetic testing for Leber hereditary optic neuropathy (LHON), were all normal or negative. Despite systemic corticosteroid therapy and plasma exchange, vision continued to worsen. Eventually, mitochondrial whole genome sequencing was performed, which demonstrated a mutation at the 13513G>A posit...
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#1Thomas Cloppenborg (Bielefeld University)H-Index: 5
#2Monique M.J. van Schooneveld (Utrecht University)H-Index: 7
Last. Kees P.J. Braun (Utrecht University)H-Index: 49
view all 9 authors...
BACKGROUND AND OBJECTIVES To (1) identify predictors of postoperative intelligence and developmental quotients (IQ/DQ) and (2) develop and validate clinically applicable IQ/DQ prediction models. METHODS We retrospectively analyzed neuropsychological outcomes and their possible determinants for children treated in Bethel and Utrecht since 1990. We performed separate analyses for patients with IQ and those with only DQ available. We developed prediction models based on presurgical determinants to ...
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