Pupillary Responses as a Biomarker of Early Risk for Alzheimer’s Disease
Abstract
Task-evoked pupillary responses may be a psychophysiological biomarker of early risk for mild cognitive impairment (MCI) and Alzheimer’s disease (AD). Pupil dilation during cognitive tasks reflects cognitive effort until compensatory capacity is surpassed and performance declines are manifest, and reflects activation in the locus coeruleus, where degenerative changes have been found in the earliest stages of AD. We recorded pupillary responses...
Paper Details
Title
Pupillary Responses as a Biomarker of Early Risk for Alzheimer’s Disease
Published Date
Feb 20, 2017
Volume
56
Issue
4
Pages
1419 - 1428
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