Review paper
Mechanisms of radiotherapy-associated cognitive disability in patients with brain tumours
Abstract
The majority of patients who receive radiotherapy for brain tumours go on to develop disability, but the pathophysiological mechanisms of radiation-associated cognitive decline remains poorly understood. Here, Makale and colleagues review animal model and patient data on the mechanisms of radiotherapy-associated CNS damage and posit that early damage — occurring before 6 months after irradiation — contributes to long-term cognitive disability....
Paper Details
Title
Mechanisms of radiotherapy-associated cognitive disability in patients with brain tumours
Published Date
Dec 16, 2016
Journal
Volume
13
Issue
1
Pages
52 - 64
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