Anti-Coagulation Agents Provide a Mechanism to Inhibit Tumor Cells From Hijacking the Angiogenic Potential of Platelets

1149 While an association between cancer and platelets has been long recognized, the cause and effect relationship linking the two remains unclear. Provocatively, recent studies suggest that anti-platelet agents can increase overall survival and decrease metastatic disease in cancer patients. Because angiogenesis is crucial for tumor growth beyond 1–2 mm3, one view is that platelets may regulate new blood vessel growth through release of the...