Ovariectomy induces oxidative stress and impairs bone antioxidant system in adult rats
Abstract
There is increasing evidence suggesting the role of free radicals in bone resorption and bone loss. Ovariectomized rats have been used as the animal model for the study of osteoporosis. Oxidative stress due to reactive oxygen species (ROS) can cause oxidative damage to cells. Cells have a number of defense mechanisms to protect themselves from the toxicity of ROS. Even though, there are studies portraying the role of free radicals in bone loss,...
Paper Details
Title
Ovariectomy induces oxidative stress and impairs bone antioxidant system in adult rats
Published Date
Oct 1, 2005
Journal
Volume
360
Issue
1-2
Pages
81 - 86
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