A 7‐Day Mouse Model to Assess Protection from Sulfur Mustard (SM) Skin Injury

Volume: 22, Issue: 4, Pages: 231 - 242
Published: Jan 1, 2003
Abstract
The mouse ear vesicant model (MEVM) is a screening tool used to identify protective compounds against acute sulfur mustard (SM)‐induced skin injury. It provides endpoints of edema and histopathology 24 h following a topical SM exposure to assess protection against inflammation and tissue damage. To further evaluate successful compounds, the MEVM was modified for use as a 7‐day model. Dose response studies were conducted with SM to select an...
Paper Details
Title
A 7‐Day Mouse Model to Assess Protection from Sulfur Mustard (SM) Skin Injury
Published Date
Jan 1, 2003
Volume
22
Issue
4
Pages
231 - 242
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