Relapsing Polychondritis Followed Up with FDG-PET.

Published on Jan 1, 2015in Internal Medicine1.005
· DOI :10.2169/INTERNALMEDICINE.54.3752
Hideharu Hagiya13
Estimated H-index: 13
(Okayama University),
Koichi Waseda9
Estimated H-index: 9
(Okayama University),
Fumio Otsuka35
Estimated H-index: 35
(Okayama University)
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Abstract Relapsing polychondritis (RPC) is a rare immune mediated disease which is associated with inflammation in cartilaginous tissue throughout the body. Especially the cartilaginous structures of ear, nose, joints and respiratory tract are affected. In around 30% of the cases an association with other diseases especially systemic vasculitis or myelodysplatic syndrome can be detected. The relative rarity of RPC has not permitted clinical trials to determine the efficacy and safety of therapy ...
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: A 78-year-old man had fever, persistent wheezing, and serum C-reactive protein elevation. Malignant lymphoma was suspected because of mediastinal lymph nodes swelling on CT and soluble interleukin 2 receptor elevation. Symmetric F-FDG uptake in the tracheobronchial tree and bilateral auricles was observed on PET/CT. He was finally diagnosed as having relapsing polychondritis by auricular cartilage biopsy. F-FDG PET/CT may have crucial role in evaluating the extent of inflammation and deciding ...
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Objective:This study aimed to evaluate fluorine-18 fludeoxyglucose positron emission tomography-CT (18F-FDG PET-CT) for the diagnosis, targeted biopsy and therapy of relapsing polychondritis (RP).Methods:The literature pertaining to the use of 18F-FDG PET-CT in patients with RP was retrieved from the Cochrane Library, PubMed, Excerpta Medica Database (EMBASE), China National Knowledge Infrastructure (CNKI) and Wanfang databases until July 2015. Clinical characteristics, auxiliary examination res...
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