Fumio Otsuka
Okayama University
Internal medicineRadiologyEndocrinologySurgeryPathologyDermatologyReceptorBone morphogenetic protein 6ChemistryGranulosa cellAldosteronePituitary adenomaAngiotensin IIBone morphogenetic proteinBone morphogenetic protein 15MedicineBMPR2BiologyGastroenterologyCell biology
402Publications
35H-index
5,830Citations
Publications 395
Newest
#1Koichiro Yamamoto (Okayama University)
#2Kosuke Oka (Okayama University)H-Index: 2
Last. Fumio Otsuka (Okayama University)H-Index: 35
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#1Yuki Otsuka (Okayama University)H-Index: 1
#2Hideharu Hagiya (Okayama University)H-Index: 5
Last. Fumio Otsuka (Okayama University)H-Index: 35
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The gold standard for the diagnosis of coronavirus disease 2019 (COVID-19) is a nucleic acid detection test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which may occasionally reveal false-positive or false-negative results. Herein, we describe a case of a patient infected with human coronavirus NL63 (HCoV-NL63) who was falsely diagnosed with COVID-19 using the Ampdirect™ 2019-nCoV detection kit (Shimadzu Corporation, Japan) and SARS-CoV-2 Detection Kit (TOYOBO co., ltd.), a...
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#1Kosuke Oka (Okayama University)H-Index: 2
#2Jo Araki (Okayama University)
Last. Fumio Otsuka (Okayama University)H-Index: 35
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#1Atsuhito Suyama (Okayama University)
#2Nahoko Iwata (Okayama University)H-Index: 5
Last. Fumio Otsuka (Okayama University)H-Index: 35
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#1Yuki Otsuka (Okayama University)H-Index: 1
#2Yasuhiro Nakano (Okayama University)H-Index: 3
Last. Fumio Otsuka (Okayama University)H-Index: 35
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#1Chiaki Kashino (Okayama University)
#2Toru Hasegawa (Okayama University)H-Index: 3
Last. Fumio Otsuka (Okayama University)H-Index: 35
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To elucidate the impact of glucocorticoids on ovarian steroidogenesis and its molecular mechanism by focusing on bone morphogenetic proteins (BMPs), we examined the effect of dexamethasone (Dex) on estradiol and progesterone synthesis by using primary culture of rat granulosa cells. It was revealed that Dex treatment dose-dependently decreased estradiol production but increased progesterone production induced by follicle-stimulating hormone (FSH) by granulosa cells. In accordance with the effect...
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#1Koichiro Yamamoto (Okayama University)
#2Manami Fujita (Okayama University)
Last. Fumio Otsuka (Okayama University)H-Index: 35
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#1Koichiro Yamamoto (Okayama University)
#2Kosuke Oka (Okayama University)H-Index: 2
Last. Fumio Otsuka (Okayama University)H-Index: 35
view all 5 authors...
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#1Ryosuke Takase (Okayama University)
#2Hideharu Hagiya (Okayama University)H-Index: 11
Last. Fumio Otsuka (Okayama University)H-Index: 35
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A 75-year-old man with well-controlled type 2 diabetes was referred to our department because of urinary obstruction. He developed retroperitoneal fibrosis 1 year prior to the referral and underwent a ureteral stent insertion at that time. Around the same period, double vision and eyelid ptosis of the right eye coincidentally appeared (figure 1A). We performed MRI of the orbit; it revealed bilateral lacrimal enlargement, especially at the right side (figure 1B, C …
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#1Satoshi Fujisawa (Okayama University)H-Index: 3
#2Motoshi Komatsubara (Okayama University)H-Index: 5
Last. Fumio Otsuka (Okayama University)H-Index: 35
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Orexin is expressed mainly in the hypothalamus and is known to activate the hypothalamic-pituitary-adrenal (HPA) axis that is involved in various stress responses and its resilience. However, the effects of orexin on the endocrine function of pituitary corticotrope cells remain unclear. In this study, we investigated the roles of orexin A in pro-opiomelanocortin (POMC) transcription using mouse corticotrope AtT20 cells, focusing on the bone morphogenetic protein (BMP) system expressed in the pit...
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