Mutational fingerprints reconstruct human cell genealogies
Abstract
Four new reports uncover the lineage relationships between cells throughout the body using mutations in the genome as cellular barcodes. The mutational composition of different tissues provides insights into both developmental processes and organ homeostasis, and may have important implications for our understanding of hereditary diseases such as polycystic kidney...
Paper Details
Title
Mutational fingerprints reconstruct human cell genealogies
Published Date
Oct 27, 2021
Journal
Volume
18
Issue
1
Pages
6 - 7
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Notes
History