Nature Reviews Nephrology
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28.31
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2,924
Papers 2,873
1 page of 288 pages (2,873 results)
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#1Saraladevi Naicker (Wits: University of the Witwatersrand)H-Index: 30
To quote Nelson Mandela, “education is the most powerful weapon which you can use to change the world”. Education and training have changed the world of nephrology in Africa for many patients and their physicians, but most low- and middle-income countries still lack access to affordable therapies for kidney disease.
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#1Nwamaka D. Eneanya (University of Pennsylvania)H-Index: 14
#2L. Ebony Boulware (Duke University)H-Index: 45
Last. Keith C. Norris (UCLA: University of California, Los Angeles)H-Index: 77
view all 15 authors...
Chronic kidney disease is an important clinical condition beset with racial and ethnic disparities that are associated with social inequities. Many medical schools and health centres across the USA have raised concerns about the use of race — a socio-political construct that mediates the effect of structural racism — as a fixed, measurable biological variable in the assessment of kidney disease. We discuss the role of race and racism in medicine and outline many of the concerns that have been ra...
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#1Xiaonan H. Wang (Emory University)H-Index: 32
#2William E. Mitch (BCM: Baylor College of Medicine)H-Index: 61
Last. S. Russ Price (ECU: East Carolina University)H-Index: 33
view all 3 authors...
Loss of muscle proteins is a deleterious consequence of chronic kidney disease (CKD) that causes a decrease in muscle strength and function, and can lead to a reduction in quality of life and increased risk of morbidity and mortality. The effectiveness of current treatment strategies in preventing or reversing muscle protein losses is limited. The limitations largely stem from the systemic nature of diseases such as CKD, which stimulate skeletal muscle protein degradation pathways while simultan...
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#1Lisa Seufert (University of Cologne)H-Index: 3
#2Thomas Benzing (University of Cologne)H-Index: 63
Last. Roman-Ulrich Müller (University of Cologne)H-Index: 23
view all 4 authors...
RNA-binding proteins (RBPs) are of fundamental importance for post-transcriptional gene regulation and protein synthesis. They are required for pre-mRNA processing and for RNA transport, degradation and translation into protein, and can regulate every step in the life cycle of their RNA targets. In addition, RBP function can be modulated by RNA binding. RBPs also participate in the formation of ribonucleoprotein complexes that build up macromolecular machineries such as the ribosome and spliceos...
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#1Parker C. Wilson (WUSTL: Washington University in St. Louis)H-Index: 9
#2Benjamin D. Humphreys (WUSTL: Washington University in St. Louis)H-Index: 68
Four new reports uncover the lineage relationships between cells throughout the body using mutations in the genome as cellular barcodes. The mutational composition of different tissues provides insights into both developmental processes and organ homeostasis, and may have important implications for our understanding of hereditary diseases such as polycystic kidney disease.
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