Deferoxamine to Minimize Fibrosis During Radiation Therapy
Abstract
Significance: By 2030, there will be >4 million radiation-treated cancer survivors living in the United States. Irradiation triggers inflammation, fibroblast activation, and extracellular matrix deposition in addition to reactive oxygen species generation, leading to a chronic inflammatory response. Radiation-induced fibrosis (RIF) is a progressive pathology resulting in skin pigmentation, reduced elasticity, ulceration and dermal thickening,...
Paper Details
Title
Deferoxamine to Minimize Fibrosis During Radiation Therapy
Published Date
Oct 1, 2022
Journal
Volume
11
Issue
10
Pages
548 - 559
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Notes
History