Advances in wound care
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2.81
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548
Papers 594
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Newest
#1Biraja C. Dash (Yale University)H-Index: 16
#2Laxminarayana Korutla (Yale University)
Last. Henry C. Hsia (Yale University)H-Index: 13
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SIGNIFICANCE Non-healing wounds are a significant burden for the healthcare system all over the world. Existing treatment options are not enough to promote healing, highlighting the urgent need for improved therapies. In addition, the current advancements in tissue-engineered skin constructs and stem cell-based therapies are facing significant hurdles due to the absence of a renewable source of functional cells. Recent Advances: Induced pluripotent stem cell technology (iPSC) is emerging as a no...
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#1Jerry F. Hsu (SC: University of Southern California)
#2Roy P. Yu (SC: University of Southern California)H-Index: 3
Last. Alexander Wong (SC: University of Southern California)H-Index: 55
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Significance null Secondary lymphedema is a debilitating disease caused by lymphatic dysfunction characterized by chronic swelling, dysregulated inflammation, disfigurement, and compromised wound healing. Since there is no effective cure, animal model systems that support basic science research into the mechanisms of secondary lymphedema are critical to advancing the field. Recent Advances: Over the last decade, lymphatic research has led to the improvement of existing animal lymphedema models a...
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#1Maximillian A. Weigelt (UM: University of Miami)H-Index: 2
#2Hadar Lev-Tov (UM: University of Miami)H-Index: 17
Last. Ira M. Herman (Tufts University)H-Index: 55
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Significance Non-healing wounds are an ever-growing global pandemic with mortality rates and management costs exceeding many common cancers. Although our understanding of the molecular and cellular...
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#1Stephen Lee Viviano (UW: University of Washington)
#2Peter C. Neligan (UW: University of Washington)H-Index: 49
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#1Heather M. Powell (OSU: Ohio State University)H-Index: 22
#2Bernadette Nedelec (McGill University)H-Index: 26
SIGNIFICANCE The physical and psychological sequalae of burn injuries account for 10 million disability-adjusted life years lost annually. Hypertrophic scarring (HSc) following burn injury results in reduced mobility, contracture, pain, itching, and aesthetic changes for burn survivors. Despite the prevalence of scarring and the number of scar therapies available, none are highly effective at preventing HSc following burn injury. Recent Advances: Recent studies modulating the mechanical environm...
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#1Javier Aragón-Sánchez (Telefónica)H-Index: 22
Last. Christian Murillo-VargasH-Index: 2
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Objective We hypothesized that patients with poor glycemic control undergoing treatment for diabetic foot infections (DFIs) would have a poorer prognosis than those with better metabolic control assessed by glycated hemoglobin (HbA1c). Approach We analyzed a retrospective cohort of 245 patients with moderate and severe DFIs. HbA1c values were dichotomized ( P75) to analyze patient outcomes regarding metabolic control. The present study adhered to the STROBE guidelines for cohort studies. Results...
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#1Ruth Tevlin (Stanford University)H-Index: 15
#2Michael T. Longaker (Stanford University)H-Index: 137
Last. Derrick C. Wan (Stanford University)H-Index: 37
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Significance By 2030, there will be over 4 million radiation-treated cancer survivors living in the US. Irradiation triggers inflammation, fibroblast activation, and extracellular matrix deposition in addition to reactive oxygen species (ROS) generation, leading to a chronic inflammatory response. Radiation-induced fibrosis (RIF) is a progressive pathology resulting in skin pigmentation, reduced elasticity, ulceration and dermal thickening, cosmetic deformity, pain, and the need for reconstructi...
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#1Ran Yan (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 2
#2Xi Fu (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 1
Last. Yi-Fang Jiang (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 1
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OBJECTIVE Even though ketorolac-infiltration is said to provide superior postoperative analgesic benefits in different surgical procedures, its safety and efficacy remain to be validated by the lack of high-quality evidence. We aimed to summarize the efficacy and safety of ketorolac-infiltration based on published randomized‑controlled trials (RCTs). APPROACH This work followed PRISMA guidelines, AMSTAR and the Cochrane Collaboration recommendations. We searched for RCTs evaluating the efficacy ...
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#1Soledad Pérez-Amodio (UPC: Polytechnic University of Catalonia)H-Index: 6
Last. Elisabeth Engel (UPC: Polytechnic University of Catalonia)H-Index: 31
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OBJECTIVE Wound healing is a complex process that involves the interaction between different cell types and bioactive factors. Impaired wound healing is characterized by a loss in synchronization of these interactions, resulting in non-healing chronic wounds. Chronic wounds are a socioeconomic burden, one of the most prominent clinical manifestations of diabetes however, they lack satisfactory treatment options. The objective of this study was to develop polymeric composites that deliver ions ha...
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#1Alicia D Menchaca (Nationwide Children's Hospital)
#2Candace C Style (Nationwide Children's Hospital)
Last. Oluyinka O. Olutoye (OSU: Ohio State University)H-Index: 1
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Significance: This body of work gives a concise and comprehensive overview for the clinician and scientist on the latest treatment modalities for hypertrophic scars (HTS) and keloids in the pediatr...
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Top fields of study
Surgery
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Wound healing
Wound care
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Medicine
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