Original paper
Transcriptomic organization of the human brain in post-traumatic stress disorder
Abstract
Despite extensive study of the neurobiological correlates of post-traumatic stress disorder (PTSD), little is known about its molecular determinants. Here, differential gene expression and network analyses of four prefrontal cortex subregions from postmortem tissue of people with PTSD demonstrate extensive remodeling of the transcriptomic landscape. A highly connected downregulated set of interneuron transcripts is present in the most...
Paper Details
Title
Transcriptomic organization of the human brain in post-traumatic stress disorder
Published Date
Dec 21, 2020
Journal
Volume
24
Issue
1
Pages
24 - 33