Original paper

YAP activation in melanoma contributes to anoikis resistance and metastasis

Volume: 246, Issue: 8, Pages: 888 - 896
Published: Dec 13, 2020
Abstract
Melanoma is inherently heterogeneous, providing resistance to apoptosis. Anoikis resistance is a hallmark feature of metastatic melanoma to escape apoptosis when cells lose contact with adjacent cells or extracellular matrix. The yes-associated protein transcription co-activator is the effector of Hippo pathway. Herein, we investigated the function of yes-associated protein in anoikis resistance of melanoma cells. When melanoma cells were grown...
Paper Details
Title
YAP activation in melanoma contributes to anoikis resistance and metastasis
Published Date
Dec 13, 2020
Volume
246
Issue
8
Pages
888 - 896
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