Original paper
The overlap between Alzheimer's disease and epilepsy uncovered by transcriptome sequencing
Abstract
Dear editor, We conducted a combinated analysis of the hippocampal transcriptome of Alzheimer's disease (AD) and epilepsy mice for the first time. Our study found that TNF-α-HIF-1-NF-κB pathway axis and circadian rhythm pathway are involved in the pathogenesis of AD and epilepsy. Most importantly, FZD7 is remarkable upregulated in the hippocampus of APP/PS1 mice and the temporal cortex of humans, which suggests that FZD7 maybe an important...
Paper Details
Title
The overlap between Alzheimer's disease and epilepsy uncovered by transcriptome sequencing
Published Date
Sep 1, 2020
Volume
10
Issue
5
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