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Original paper

SLC25A51 is a mammalian mitochondrial NAD+ transporter

Nature50.50
Volume: 588, Issue: 7836, Pages: 174 - 179
Published: Sep 9, 2020
Abstract
Mitochondria require nicotinamide adenine dinucleotide (NAD+) to carry out the fundamental processes that fuel respiration and mediate cellular energy transduction. Mitochondrial NAD+ transporters have been identified in yeast and plants1,2, but their existence in mammals remains controversial3–5. Here we demonstrate that mammalian mitochondria can take up intact NAD+, and identify SLC25A51 (also known as MCART1)—an essential6,7...
Paper Details
Title
SLC25A51 is a mammalian mitochondrial NAD+ transporter
Published Date
Sep 9, 2020
Journal
Volume
588
Issue
7836
Pages
174 - 179
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