ESGE suggests endoscopic therapy and/or extracorporeal shockwave lithotripsy (ESWL) as the first-line therapy for painful uncomplicated chronic pancreatitis (CP) with an obstructed main pancreatic duct (MPD) in the head/body of the pancreas. The clinical response should be evaluated at 6 – 8 weeks; if it appears unsatisfactory, the patient’s case should be discussed again in a multidisciplinary team and surgical options should be considered. Weak recommendation, low quality evidence. ESGE sugges...
#1Zhen-Hua Zhao('SMMU': Second Military Medical University)H-Index: 3
#2Liang-Hao Hu('SMMU': Second Military Medical University)H-Index: 17
Last. Zhuan Liao('SMMU': Second Military Medical University)H-Index: 19
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Background and Aims Almost all studies on post-ERCP pancreatitis (PEP) have mainly involved patients with biliary diseases rather than chronic pancreatitis (CP), and the concept that CP seems to be a protective factor associated with PEP has not been studied in detail. The aim of this study was to determine the incidence of PEP in patients with CP at different clinical stages and to identify the predictive and protective factors of PEP in a large cohort. Methods In this observational cohort stud...
BackgroundThere have been substantial improvements in the management of chronic pancreatitis, leading to the publication of several national guidelines during recent years. In collaboration with United European Gastroenterology, the working group on ‘Harmonizing diagnosis and treatment of chronic pancreatitis across Europe’ (HaPanEU) developed these European guidelines using an evidence-based approach.MethodsTwelve multidisciplinary review groups performed systematic literature reviews to answer...
#1Bai-Rong Li('SMMU': Second Military Medical University)H-Index: 9
#2Zhuan Liao('SMMU': Second Military Medical University)H-Index: 15
Last. Zhao-Shen Li('SMMU': Second Military Medical University)H-Index: 60
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Background and study aims: Extracorporeal shock wave lithotripsy is recommended as treatment for stones in chronic pancreatitis. The aim of this study was to investigate the risk factors for complications of pancreatic extracorporeal shock wave lithotripsy (P-ESWL). Patients and methods: Patients with painful chronic pancreatitis and pancreatic stones (> 5 mm diameter) who were treated with P-ESWL between March 2011 and June 2013 were prospectively included. Adverse events after P-ESWL were clas...
#2Adam Slivka(University of Pittsburgh)H-Index: 61
Last. Dhiraj Yadav(University of Pittsburgh)H-Index: 51
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Background & Aims Endoscopic therapy (ET) frequently is used to treat patients with painful chronic pancreatitis (CP), but little is known about outcomes of patients for whom ET was not successful who then underwent surgery, or outcomes after ET compared with only medical treatment. We evaluated use and long-term effectiveness of ET in a well-defined cohort of patients with CP. Methods We analyzed data from 146 patients with CP who participated in the North American Pancreatitis Study 2 at the U...
Background Most outcomes data on pancreatic extracorporeal shock wave lithotripsy (P-ESWL) for chronic calcific pancreatitis (CCP) are based on studies with Objective To report long-term P-ESWL outcomes for CCP and to assess whether smoking or alcohol use influences P-ESWL outcomes. Design Cross-sectional study, retrospective chart review. Setting Virginia Mason Medical Center, Seattle, Washington. Patients This study involved 120 patients who underwent P-ESWL and ERCP for CCP and completed an o...
Last. Italo Vantini(University of Verona)H-Index: 36
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Abstract This paper gives practical guidelines for diagnosis and treatment of chronic pancreatitis. Statements have been elaborated by working teams of experts, by searching for and analysing the literature, and submitted to a consensus process by using a Delphi modified procedure. The statements report recommendations on clinical and nutritional approach, assessment of pancreatic function, treatment of exocrine pancreatic failure and of secondary diabetes, treatment of pain and prevention of pa...
Background & Aims: Endotherapy for patients with painful chronic pancreatitis (CP) gives early and midterm clinical results comparable with those of conventional surgery. The authors evaluated long-term clinical outcome after endoscopic pancreatic ductal drainage, focusing on pain and pancreatic endocrine/exocrine functions. Methods: Of 110 patients with painful CP endoscopically treated between October 1987 and December 1989, 56 long-surviving patients were followed-up for 14.4 years (SD, .6 y)...
Last. Pramod Kumar Garg(AIIMS: All India Institute of Medical Sciences)H-Index: 46
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Current knowledge about chronic pancreatitis (CP) is limited and there is a particular dearth of information about the entity known as tropical pancreatitis. A consensus working party was convened by the Trustees of the Journal of Gastroenterology and Hepatology Foundation to conduct a systematic investigation into available evidence about the epidemiology, etiopathogenesis, diagnosis and management of CP. A literature search and formal survey of international experts in the field were used to a...