Digestive and Liver Disease
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#1Maria GuarinoH-Index: 20
#2V. CossigaH-Index: 6
Last. Filomena MoriscoH-Index: 36
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Sarcopenia, defined as progressive and generalized loss of muscle mass and strength, is common in chronic liver disease. It significantly impacts the quality of life and increases the risk of liver-related complications and mortality in cirrhotic patients. Moreover, recent studies showed a negative impact of sarcopenia on patients awaiting liver transplantation (LT), on post-LT outcomes, and on response to hepatocellular carcinoma therapies. Data about the influence of sex on the incidence, prev...
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#1Qing-Ling Chen (Jilin University)
#2Rui Zhong (Jilin University)
Last. Qinglong Jin (Jilin University)H-Index: 2
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Abstract null null Background null Whether the anti-gp210 antibody can be used as a biomarker in patients with primary biliary cholangitis (PBC) remains controversial. null null null Aims null We aimed to investigate the association between anti-gp210 antibodies and prognosis in ursodeoxycholic acid (UDCA)-treated PBC patients. null null null Methods null We conducted a retrospective cohort study of 180 UDCA-treated PBC patients to assess the prognostic value of anti-gp210 antibodies using the K...
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#1Corey J. Ketchem (UNC: University of North Carolina at Chapel Hill)H-Index: 1
#2Kisan Thakkar (UNC: University of North Carolina at Chapel Hill)H-Index: 1
Last. Evan S. Dellon (UNC: University of North Carolina at Chapel Hill)H-Index: 71
view all 12 authors...
Abstract null null Background null There are few data assessing treatment response in older eosinophilic esophagitis (EoE) patients and we evaluated treatment outcomes to topical corticosteroids (tCS) in this older population. null null null Methods null This retrospective cohort study of the UNC EoE Clinicopathologic database included subjects with a new diagnosis of EoE treated with tCS. Histologic responses, global symptom response, and endoscopic changes were recorded. Older EoE patients (≥6...
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#1Ma Teng (Fudan University)
#2Jie Gu (Fudan University)
Last. Duowu Zou (SJTU: Shanghai Jiao Tong University)
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Abstract null null Background null PPI-refractory gastroesophageal reflux disease (RGERD) is characterized as the existence of reflux symptoms resistant to optimized PPI treatment. Alleviated mucosal integrity has been regarded as one of the mechanisms of RGERD. null null null Methods null RNA sequencing analysis and GSEA were performed. Human biopsy samples, cell lines, and rat models were recruited. Trans-epithelial electrical resistance (TEER) was tested and a FITC-dextran flux assay was perf...
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#1Voytek Slowik (UMKC: University of Missouri–Kansas City)H-Index: 5
#2Tassos Grammatikopoulos (KCL: King's College London)H-Index: 12
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#1Suprabhat GiriH-Index: 1
#2Sridhar Sundaram (TMC: Tata Memorial Hospital)H-Index: 1
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#1Le Bao (CUMT: China University of Mining and Technology)
Last. Jian Liu
view all 7 authors...
Abstract null null Background null Pseudogenes are dysfunctional copies of protein-coding genes that showed critical regulatory roles during carcinogenesis. Plasminogen like A (PLGLA) is a transcribed unprocessed pseudogene and biasedly expressed in liver. But its function has not been studied in hepatocellular carcinoma (HCC). null null null Aims null We aimed to explore the role of PLGLA in HCC. null null null Methods null The expression of PLGLA and its association with pathological features ...
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#1Sahaj Rathi (PGIMER: Post Graduate Institute of Medical Education and Research)H-Index: 12
#2Silvia Brocco (UNIPD: University of Padua)H-Index: 2
Last. Piero Amodio (UNIPD: University of Padua)H-Index: 50
view all 11 authors...
Background Spontaneous portosystemic shunts (SPSS) are common in cirrhosis. Their characterization and clinical implications remain unclear. Aims To devise a system of assessment of these shunts, and assess their clinical implications METHODS: We retrospectively studied patients with cirrhosis who underwent imaging in a liver transplant program. A novel index was computed to assess total SPSS -the diameter of a circle having an area equivalent to the sum of the areas of all the existing shunts. ...
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#1Riccardo De CarlisH-Index: 12
#2Vincenzo BuscemiH-Index: 8
Last. Luciano De Carlis (UNIMIB: University of Milano-Bicocca)H-Index: 32
view all 4 authors...
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