Original paper
Sex-dependent autosomal effects on clinical progression of Alzheimer’s disease
Abstract
Sex differences in the manifestations of Alzheimer’s disease are under intense investigation. Despite the emerging importance of polygenic predictions for Alzheimer’s disease, sex-dependent polygenic effects have not been demonstrated. Here, using a sex crossover analysis, we show that sex-dependent autosomal genetic effects on Alzheimer’s disease can be revealed by characterizing disease progress via the hazard function. We first performed...
Paper Details
Title
Sex-dependent autosomal effects on clinical progression of Alzheimer’s disease
Published Date
Jun 27, 2020
Journal
Volume
143
Issue
7
Pages
2272 - 2280
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Notes
History