External Validation of a Predictive Model of Urethral Strictures for Prostate Patients Treated With HDR Brachytherapy Boost

Purpose:For prostate cancer treatment, comparable or superior biochemical control was reported when using External-Beam-Radiotherapy(EBRT) with High-Dose-Rate-Brachytherapy(HDRB)-boost, compared to dose-escalation with EBRT alone. The conformal doses produced by HDRB could allow further beneficial prostate dose-escalation, but increase in dose is limited by normal tissue toxicity. Previous works showed correlation between urethral dose and...