Matrix Metalloproteinase 9 (MMP9) Inhibitor Prevents Mustard Induced Microvesication and Promotes Cutaneous Wound Healing

Skin exposure to the chemical warfare agent, sulfur mustard (bis‐2‐chloroethylsulfide, SM), is characterized by severe blister formation and a prolonged inflammatory response. The mechanisms of these SM toxic effects are still poorly defined, and effective medical countermeasures against SM‐induced cutaneous injury have yet to be established. Animal models demonstrate disruption of the skin architecture at the dermal‐epidermal junction (DEJ)...