Immunostimulatory effects on THP-1 cells by peptide or protein pharmaceuticals associated with injection site reactions
Abstract
Injection site reaction (ISR) is a common side-effect associated with the use of peptide or protein pharmaceuticals. These types of pharmaceuticals-induced activation of antigen-presenting cells is assumed to be a key step in the pathogenesis of immune-mediated ISR. The present study was designed to evaluate the immunostimulatory properties of peptide or protein pharmaceuticals using human monocytic THP-1 cells. Here, THP-1 cells, with or...
Paper Details
Title
Immunostimulatory effects on THP-1 cells by peptide or protein pharmaceuticals associated with injection site reactions
Published Date
Jan 1, 2020
Journal
Volume
17
Issue
1
Pages
59 - 66
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