Improved delivery of doxorubicin using rationally designed PEGylated platinum nanoparticles for the treatment of melanoma
Abstract
Efficient delivery of chemotherapeutic drugs to tumor cells is one of the crucial issues for modern day cancer therapy. In this article, we report the synthesis of poly ethylene glycol (PEG) assisted colloidal platinum nanoparticles (PtNPs) by borohydride reduction method at room temperature. PtNPs are stable at room temperature for more than 2 years and are stable in serum and phosphate buffer (pH = 7.4) solution for one week. PtNPs show...
Paper Details
Title
Improved delivery of doxorubicin using rationally designed PEGylated platinum nanoparticles for the treatment of melanoma
Published Date
Mar 1, 2020
Volume
108
Pages
110375 - 110375
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