Materials Science and Engineering: C
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#1Fanjin Wang (UCL: University College London)H-Index: 1
#2Moe Elbadawi (UCL: University College London)H-Index: 9
Last. Maryam Parhizkar (UCL: University College London)H-Index: 13
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Abstract null null Electrohydrodynamic (EHD) processes are promising healthcare fabrication technologies, as evidenced by the number of commercialised and food-and-drug administration (FDA)-approved products produced by these processes. Their ability to produce both rapidly and precisely nano-sized products provides them with a unique set of qualities that cannot be matched by other fabrication technologies. Consequently, this has stimulated the development of EHD processing to tackle other heal...
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#1Wendi Ma (Jilin University)H-Index: 3
#2Wenying Dong (Jilin University)H-Index: 3
Last. Mei Zhang (Jilin University)H-Index: 7
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Abstract null null It's an exigent need for the improvement of novel antibacterial wound dressings with the increasing threats of drug resistance caused by excessive use of the antibiotics. In this work, an injectable, adhesive, hemostatic, biocompatible and bactericidal hydrogel wound dressing was fabricated. An injectable hydrogel can fill the irregular wound due to the characteristic of reversible sol-gel transition, whereas conventional dressings don't possess this ability. Oxidized alginate...
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#1Qianyun Li (HUST: Huazhong University of Science and Technology)
#2Kun Liu (WUT: Wuhan University of Technology)H-Index: 2
Last. Zhen-bing Chen (HUST: Huazhong University of Science and Technology)H-Index: 9
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Abstract null null The difficulty of wound healing in patients with diabetes mellitus remains a considerable challenge for clinical and scientific research. To address the problem of poor healing that affects chronic wounds in patients with diabetes, we developed an injectable self-healing hydrogel based on chitosan (CS), hyaluronic acid (HA), and kalium γ-cyclodextrin metal organic frameworks (K-γ-CD-MOFs) loaded α-lipoic acid (α-LA) with antibacterial activity and antioxidant performance. In v...
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#1Anguluri N V Lakshmi Kavya (Amity University)H-Index: 1
#2Sundarrajan Subramanian (NUS: National University of Singapore)H-Index: 2
Last. Seeram Ramakrishna (NUS: National University of Singapore)H-Index: 136
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Abstract null null Exosomes (30–150 nm in diameter) a subset of extracellular vesicles, secreted by mostly all cells, have been gaining enormous recognition from the last decade. In recent times, several studies have included exosomes to design novel therapeutic applications along with their contribution to diagnostic evaluations and pathophysiological processes. Based on cell origin, they show diverse functions and characteristics. This article is classified into several sections that include e...
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#1Xinbo Wei (BUAA: Beihang University)
#2Depeng Yang (HIT: Harbin Institute of Technology)
Last. Haifeng Liu (BUAA: Beihang University)H-Index: 27
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Abstract null null Quercetin (Que) has been proved to have various biological activities, including anti-oxidation, anti-inflammation and anti-virus, showing great potential in liver protection. However, its water insolubility leads to low bioavailability. Therefore, the development of a suitable drug delivery fashion is imminent. In recent years, liposomes have been widely used in the fields of drug delivery and gene transfer thanks to the cell membrane like structure, easy surface-modification...
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#1Diego Pacheco Wermuth (UFRGS: Federal University of Rio Grande do Sul)H-Index: 1
#2Thaís Casagrande Paim (UFCSPA: Universidade Federal de Ciências da Saúde de Porto Alegre)H-Index: 3
Last. Camila Ferreira Escobar (UFRB: Federal University of Recôncavo da Bahia)H-Index: 1
view all 13 authors...
Abstract null null Metal injection molding (MIM) has become an important manufacturing technology for biodegradable medical devices. As a biodegradable metal, pure iron is a promising biomaterial due to its mechanical properties and biocompatibility. In light of this, we performed the first study that manufactured and evaluated the in vitro and in vivo biocompatibility of samples of iron porous implants produced by MIM with a new eco-friendly feedstock from natural rubber (Hevea brasiliensis), a...
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#1B.R. Spirandeli (UNIFESP: Federal University of São Paulo)H-Index: 1
Last. Eliandra de Sousa Trichês (UNIFESP: Federal University of São Paulo)H-Index: 8
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Abstract null null In this work, β-TCP (β-tricalcium phosphate) bioresorbable scaffolds were prepared by the gel casting method. Then, they were impregnated with a 45S5 bioglass sol gel solution to improve biocompatibility and promote bioactivity and antimicrobial activity. The β-TCP scaffolds had an apparent porosity of 72%, and after the incorporation of the bioglass, this porosity was maintained. The elements of the bioglass were incorporated into β-TCP matrix and there was a partial transfor...
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#1Jian-Chun Lin (SMU: Southern Medical University)H-Index: 1
#2Daorong Xu (SMU: Southern Medical University)
Last. Bin Yu (SMU: Southern Medical University)H-Index: 22
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Abstract null null To improve the osteoinductivity, antibacterial activity, and clinical application of calcium sulfate hemihydrate (CSH), carboxymethyl chitosan zinc (CMCS-Zn) and α-CSH were prepared using different mass ratios. The setting time and injectability of the CMCS-Zn/α-CSH composite were increased with increasing CMCS-Zn content. After adding different amounts of CMCS-Zn to α-CSH, the fine lamellar structure of CMCS-Zn was found by scanning electron microscopy (SEM), which is evenly ...
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#1Zhaohui Liu (TMU: Tianjin Medical University)H-Index: 8
#2Yan Li (TMU: Tianjin Medical University)H-Index: 2
Last. Min Qu (TMU: Tianjin Medical University)H-Index: 4
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Abstract null null Ischemia-reperfusion (I/R) injury causes high morbidity, mortality, and healthcare costs. I/R induces acute kidney injury through exacerbating the mitochondrial damage and increasing inflammatory and oxidative responses. Here, we developed the mitochondria-targeted nanocarrier to delivery of Coenzyme Q10 (CoQ10) for renal I/R treatment in animal model. The mitochondria-targeted TPP CoQ10 nanoparticles (T-NPCoQ10) were synthesized through ABC miktoarm polymers method and charac...
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#1Teliang Lu (SCUT: South China University of Technology)H-Index: 7
#2Jing ZhangH-Index: 10
Last. Jiandong Ye (SCUT: South China University of Technology)H-Index: 32
view all 8 authors...
Abstract null null Calcium phosphate cement (CPC) with good injectability and osteoconductivity plays important roles in bone grafting application. Much attention has been paid to achieve multifunctionality through incorporating trace elements into CPC. Silicon and zinc can be used as additives to endow CPC with biological functions of osteogenesis, angiogenesis and anti-osteoclastogenesis. In this study, zinc and silicate ions were co-incorporated into CPC through mixing with submicron zinc sil...
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