Soy isoflavones prevent bone resorption and loss, a systematic review and meta-analysis of randomized controlled trials

Osteoporosis is a common bone disease characterized by reduced bone mass resulting from continuous bone resorption.PubMed, Scopus, and Embase were searched to find published trials on the effect of soy isoflavones on bone mineral density (BMD) and bone turnover markers (bone-specific alkaline phosphatase, osteocalcin, osteoprotegerin, pyridinoline, deoxypyridinoline, C-telopeptide, and N-telopeptide). Random-effects inverse-variance model was...