Review paper
Animal models of monoclonal immunoglobulin-related renal diseases
Abstract
Monoclonal immunoglobulin deposition produces complex diseases with heterogeneous phenotypes, making it difficult to identify the underlying mechanisms of immunoglobulin aggregation and deposition. In this Review, the authors discuss animal models of various human immunoglobulin deposition diseases, and each model's drawbacks and contributions to our understanding of these diseases. The renal deposition of monoclonal immunoglobulins can cause...
Paper Details
Title
Animal models of monoclonal immunoglobulin-related renal diseases
Published Date
Feb 19, 2018
Journal
Volume
14
Issue
4
Pages
246 - 264