[P3-380]: CHANGES IN WHITE MATTER INTEGRITY AND CEREBRAL BLOOD FLOW IN THE EPISODIC MEMORY NETWORK IN COGNITIVELY NORMAL OLDER ADULTS WITH β-AMYLOID PATHOLOGY

A large proportion of asymptomatic older adults present beta-amyloid (Aβ) deposition, a pathological hallmark of Alzheimer's disease. Using multimodal neuroimaging measures, we assessed how Aβ deposition relates to resting-state cerebral blood flow (CBF) and white matter integrity (WMI) in brain regions critical for episodic memory among cognitively normal older adults. We assessed cerebral blood flow and white matter integrity that were...