The characterization and optimal management of high-risk pancreatic anastomoses during pancreatoduodenectomy

Objective: The utility of technical strategies to prevent clinically relevant postoperative pancreatic fistula (CR-POPF) following pancreaticoduodenectomy (PD) may vary by the circumstances of the anastomosis. The Fistula Risk Score (FRS) identifies a distinct high-risk cohort (FRS 7–10) that demonstrates substantially worse clinical outcomes. The value of various fistula mitigation strategies in these particular high-stakes cases has not been...