Matthew T. McMillan
University of Pennsylvania
Framingham Risk ScoreInterquartile rangeCancerRisk assessmentInternal medicineSurgeryOncologyRetrospective cohort studyHazard ratioSurvival rateFistulaAdjuvant therapyPancreaticoduodenectomyMEDLINEPancreatic fistulaProportional hazards modelRadiation therapyGeneral surgeryMedicineComplication
76Publications
23H-index
1,566Citations
Publications 75
Newest
#1Fabio Casciani (UPenn: University of Pennsylvania)H-Index: 2
#2Maxwell T. Trudeau (UPenn: University of Pennsylvania)H-Index: 3
Last. Ronald R. SalemH-Index: 29
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Abstract Background The association between intraoperative estimated blood loss and outcomes after pancreatoduodenectomy has, thus far, been rarely explored. Methods In total, 7,706 pancreatoduodenectomies performed at 18 international institutions composing the Pancreas Fistula Study Group were examined (2003–2020). High estimated blood loss (>700 mL) was defined as twice the median. Propensity score matching (1:1 exact-match) was employed to adjust for variables associated with high estimated ...
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#1Fabio Casciani (UPenn: University of Pennsylvania)H-Index: 2
#2Maxwell T. Trudeau (UPenn: University of Pennsylvania)H-Index: 3
Last. John W. KunstmanH-Index: 18
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Abstract Background Pancreatoduodenectomies at high risk for clinically relevant pancreatic fistula are uncommon, yet intimidating, situations. In such scenarios, the impact of individual surgeon experience on outcomes is poorly understood. Methods The fistula risk score was applied to identify high-risk patients (fistula risk score 7–10) from 7,706 pancreatoduodenectomies performed at 18 international institutions (2003–2020). For each case, surgeon pancreatoduodenectomy career volume and years...
4 CitationsSource
#1Maxwell T. Trudeau (UPenn: University of Pennsylvania)H-Index: 3
#2Laura Maggino (UPenn: University of Pennsylvania)H-Index: 10
Last. Charles M. Vollmer (UPenn: University of Pennsylvania)H-Index: 67
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Abstract Background Intraoperative drain use for pancreatoduodenectomy (PD) has been practiced in an unconditional, binary manner (placement/no-placement). Alternatively, dynamic drain management has been introduced, incorporating the Fistula Risk Score (FRS) and drain fluid amylase (DFA) analysis, to mitigate clinically-relevant pancreatic fistula (CR-POPF). Study Design An extended experience with dynamic drain management was employed at a single institution for 400 consecutive PDs (2014-2019)...
8 CitationsSource
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#1Thomas F. Seykora (UPenn: University of Pennsylvania)H-Index: 5
#2Brett L. Ecker (UPenn: University of Pennsylvania)H-Index: 18
Last. Charles M. VollmerH-Index: 67
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OBJECTIVE:The aim of this study was to elucidate the impact of intraoperative blood loss on outcomes following pancreatoduodenectomy (PD). BACKGROUND:The negative impact of intraoperative blood loss on outcomes in PD has long been suspected but not well characterized, particularly those factors that may be within surgeons' control. METHODS:From 2001 to 2015, 5323 PDs were performed by 62 surgeons from 17 institutions. Estimated blood loss (EBL) was discretized (0 to 300, 301 to 750, 751 to 1300,...
21 CitationsSource
#1Maxwell T. TrudeauH-Index: 3
#2Brett L. EckerH-Index: 18
Last. Charles M. VollmerH-Index: 67
view all 5 authors...
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#1Brett L. Ecker (UPenn: University of Pennsylvania)H-Index: 18
#2Matthew T. McMillan (UPenn: University of Pennsylvania)H-Index: 23
Last. Charles M. Vollmer (UPenn: University of Pennsylvania)H-Index: 67
view all 4 authors...
Background Improvements in surgical outcomes are predicated on recognizing effective practices with subsequent adaptation. It is unknown whether risk assessment for pancreatic fistula (clinically relevant postoperative pancreatic fistula [CR-POPF]) after pancreaticoduodenectomy (PD) translates to improved patient outcomes at the practice level. Study design A prospectively collected, single-surgeon career experience (2003 to 2018) of 455 consecutive pancreatectomies (303 PDs and 152 distal pancr...
12 CitationsSource
#1Sonam Sharma (UPenn: University of Pennsylvania)H-Index: 11
#2Matthew T. McMillan (UPenn: University of Pennsylvania)H-Index: 23
Last. Jacob E. Shabason (UPenn: University of Pennsylvania)H-Index: 11
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Abstract Introduction Patients with small-cell lung cancer (SCLC) have a high incidence of occult brain metastases and are often treated with prophylactic cranial irradiation (PCI). Despite a small survival advantage in some studies, the role of PCI in extensive stage SCLC remains controversial. We used the National Cancer Database to assess survival of patients with metastatic SCLC treated with PCI. Patients and Methods Metastatic SCLC patients without brain metastases were identified. To minim...
12 CitationsSource
#1Brett L. Ecker (UPenn: University of Pennsylvania)H-Index: 18
#2Matthew T. McMillan (UPenn: University of Pennsylvania)H-Index: 23
Last. Charles M. Vollmer (UPenn: University of Pennsylvania)H-Index: 67
view all 38 authors...
Objective:The aim of this study was to identify the optimal fistula mitigation strategy following pancreaticoduodenectomy.Background:The utility of technical strategies to prevent clinically relevant postoperative pancreatic fistula (CR-POPF) following pancreatoduodenectomy (PD) may vary by the circ
65 CitationsSource
#2Brett L. EckerH-Index: 18
Last. Charles M. VollmerH-Index: 67
view all 6 authors...
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