Original paper
Transferon™, a peptide mixture with immunomodulatory properties is not immunogenic when administered with various adjuvants
Abstract
Transferon, a human dialyzable leukocyte extract (hDLE), is a biotherapeutic that comprises a complex mixture of low-molecular-weight peptides (< 10 kDa) and is used to treat diseases with an inflammatory component. Some biotherapeutics, including those composed of peptides, can induce anti-drug antibodies (ADA) that block or diminish their therapeutic effect. Nevertheless, few studies have evaluated peptide-derived drug immunogenicity. In this...
Paper Details
Title
Transferon™, a peptide mixture with immunomodulatory properties is not immunogenic when administered with various adjuvants
Published Date
Jan 1, 2017
Journal
Volume
14
Issue
1
Pages
169 - 177