A Sterile 20 Family Kinase and Its Co-factor CCM-3 Regulate Contractile Ring Proteins on Germline Intercellular Bridges

Intercellular bridges are proposed to arise from stabilization of a mitotic cytokinetic ring. Rehain-Bell et al. demonstrate that inhibition of non-muscle myosin II is a conserved mechanism of bridge stabilization and find that, in the C. elegans oogenic germline, this is mediated by GCK-1Ste-20 Kinase, its co-factor CCM-3, and anillin...