OP0056 Association of IL-12P40 and IL-12P70 with Pathophysiology of Takayasu Arteritis

Volume: 75, Issue: Suppl 2, Pages: 75.2 - 76
Published: Jun 1, 2016
Abstract

Background

We preliminarily found a SNP (rs6871626, A vs. C) in IL-12B region as a susceptibility gene to Takayasu arteritis (TAK) by genome-wide association study. IL-12B encodes IL-12p40 that is a component of both IL-12p70 and IL-23. The significance of IL-12p40 in pathophysiology of TAK has not been fully investigated yet. Moreover, there has been no consistent evidence about whether IL-12p70 or IL-23 is important in...
Paper Details
Title
OP0056 Association of IL-12P40 and IL-12P70 with Pathophysiology of Takayasu Arteritis
Published Date
Jun 1, 2016
Volume
75
Issue
Suppl 2
Pages
75.2 - 76
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