Hajime Yoshifuji
Kyoto University
Internal medicinePathologyAntibodyDermatologyAutoantibodyHuman leukocyte antigenRheumatologyImmunologyVasculitisArthritisTocilizumabRheumatoid arthritisDermatomyositisDiseaseIgG4-related diseasePathogenesisIn patientTakayasu arteritisMedicineBiologyGastroenterology
Publications 124
#1Yoshie Gon (Kyoto University)H-Index: 2
#2Hajime Yoshifuji (Kyoto University)H-Index: 24
Last. Chikashi Terao (Kyoto University)H-Index: 31
view all 8 authors...
Objectives: Biologics have been used to treat refractory Takayasu arteritis (TAK), but their efficacy and safety have not been sufficiently evaluated.Methods: We extracted clinical information from...
3 CitationsSource
#1Mineto Ota (UTokyo: University of Tokyo)H-Index: 4
#2Yasuo Nagafuchi (UTokyo: University of Tokyo)H-Index: 11
Last. Keishi Fujio (UTokyo: University of Tokyo)H-Index: 29
view all 41 authors...
Summary Genetic studies have revealed many variant loci that are associated with immune-mediated diseases. To elucidate the disease pathogenesis, it is essential to understand the function of these variants, especially under disease-associated conditions. Here, we performed a large-scale immune cell gene-expression analysis, together with whole-genome sequence analysis. Our dataset consists of 28 distinct immune cell subsets from 337 patients diagnosed with 10 categories of immune-mediated disea...
#1Hiroshi Doi (Kyoto University)H-Index: 4
#2Koichiro Ohmura (Kyoto University)H-Index: 35
Last. Morinobu Akio (Kyoto University)
view all 17 authors...
ObjectiveThe systemic lupus erythematosus (SLE) symptom checklist (SSC) is a patient-reported outcome measure consisting of 38 queries. We translated SSC into Japanese and attempted to validate its...
#1Keiichiro Kadoba (Kyoto University)H-Index: 1
#2Ryu Watanabe (Kyoto University)H-Index: 19
Last. Hajime Yoshifuji (Kyoto University)H-Index: 24
view all 6 authors...
#1Emily Rose (NIH: National Institutes of Health)H-Index: 1
#2Marcela A. Ferrada (NIH: National Institutes of Health)H-Index: 5
Last. Peter C. Grayson (NIH: National Institutes of Health)H-Index: 25
view all 12 authors...
OBJECTIVE Relapsing polychondritis (RP) is a systemic inflammatory disorder of cartilage that lacks validated disease activity measures. Physician global assessment (PhGA), a measure of disease activity commonly used in rheumatologic diseases, has not been tested in a cohort of patients with RP. METHODS Adult patients in an observational cohort of RP underwent standardized, comprehensive evaluation at approximately 6-month intervals. PhGA was scored by three physicians from the evaluating instit...
#1Hajime Yoshifuji (Kyoto University)H-Index: 24
#2Sumika Kagebayashi (Kyoto University)
Last. Tsuneyo Mimori (Kyoto University)H-Index: 77
view all 7 authors...
Pulmonary arterial hypertension (PAH) is a rare complication of ANCA-associated vasculitis (AAV). We report a 37-year-old man with PAH complicated by both AAV and SSc who presented with dyspnea, ca...
#1Takafumi Niwamoto (Kyoto University)H-Index: 1
#2Tomohiro Handa (Kyoto University)H-Index: 27
Last. Toyohiro Hirai (Kyoto University)H-Index: 37
view all 12 authors...
AbstractObjectives: Immunoglobulin G4-related disease (IgG4-RD) is a systemic, multiorgan disease of unknown etiology. We aimed to classify IgG4-RD by a combination pattern of affected organs and i...
4 CitationsSource
#1Hideaki Tsuji (Kyoto University)H-Index: 8
#2Hajime Yoshifuji (Kyoto University)H-Index: 24
Last. Koichiro Ohmura (Kyoto University)H-Index: 35
view all 13 authors...
We report a case of 68-year-old man with stable polymyositis complicated with primary hepatic lymphoma (PHL) as other iatrogenic immunodeficiency-related lymphoproliferative disorders (OIIA-LPD). Multiple liver masses were diagnosed as diffuse large B-cell lymphoma (DLBCL) by biopsy. The LPD was associated with Epstein-Barr virus (EBV) reactivation, because EBV-DNA was detected in peripheral blood, and EBV antigen was detected in the tumour. He presented with high fever, cytopenia and hyperferri...