Tsuneyo Mimori
Kyoto University
Internal medicinePathologyAntigenMolecular biologyAntibodyAutoantibodyRheumatologyImmunologyConnective tissue diseaseArthritisInterstitial lung diseaseRheumatoid arthritisDermatomyositisAutoimmune diseaseDiseasePolymyositisMyositisMedicineBiologyGastroenterology
Publications 517
#1Hideaki Tsuji (Osaka University)H-Index: 8
#2Koichiro Ohmura (Kyoto University)H-Index: 35
Last. Yukinori Okada (Osaka University)H-Index: 64
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Objective null Specific HLA class II alleles are associated with susceptibility to systemic lupus erythematosus (SLE). The role of HLA class II molecules in SLE pathogenesis remains unclear, although anti-DNA antibodies are specific to SLE and correlate to disease activity. We previously demonstrated that misfolded proteins bound to HLA class II molecules are specific targets for the autoantibodies produced in autoimmune diseases. We hypothesized that DNA binds to HLA class II molecules in a man...
#1Mineto Ota (UTokyo: University of Tokyo)H-Index: 4
#2Yasuo Nagafuchi (UTokyo: University of Tokyo)H-Index: 11
Last. Keishi Fujio (UTokyo: University of Tokyo)H-Index: 29
view all 41 authors...
Summary Genetic studies have revealed many variant loci that are associated with immune-mediated diseases. To elucidate the disease pathogenesis, it is essential to understand the function of these variants, especially under disease-associated conditions. Here, we performed a large-scale immune cell gene-expression analysis, together with whole-genome sequence analysis. Our dataset consists of 28 distinct immune cell subsets from 337 patients diagnosed with 10 categories of immune-mediated disea...
#1Ikuko Ueda-Hayakawa (Kanazawa University)H-Index: 9
#2Manabu Fujimoto (Kanazawa University)H-Index: 83
Last. Masataka Kuwana (Nippon Medical School)H-Index: 78
view all 11 authors...
#1Hajime Yoshifuji (Kyoto University)H-Index: 23
#2Sumika Kagebayashi (Kyoto University)
Last. Tsuneyo Mimori (Kyoto University)H-Index: 77
view all 7 authors...
Pulmonary arterial hypertension (PAH) is a rare complication of ANCA-associated vasculitis (AAV). We report a 37-year-old man with PAH complicated by both AAV and SSc who presented with dyspnea, ca...
#1Takafumi Niwamoto (Kyoto University)H-Index: 1
#2Tomohiro Handa (Kyoto University)H-Index: 27
Last. Toyohiro Hirai (Kyoto University)H-Index: 37
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AbstractObjectives: Immunoglobulin G4-related disease (IgG4-RD) is a systemic, multiorgan disease of unknown etiology. We aimed to classify IgG4-RD by a combination pattern of affected organs and i...
4 CitationsSource
#1Mirei ShirakashiH-Index: 4
#2Ran NakashimaH-Index: 21
Last. Tsuneyo MimoriH-Index: 77
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OBJECTIVES: Rapidly progressive interstitial lung disease (RP-ILD) with poor prognosis often accompanies anti-melanoma differentiation-associated gene 5 (MDA5)-positive DM. Combined immunosuppressive therapy, including glucocorticoids, calcineurin inhibitors and intravenous cyclophosphamide (IVCY) is reportedly effective in DM with RP-ILD, but some patients remain resistant to therapy. We examined the utility of plasma exchange (PE) in such intractable cases and investigated the prognostic facto...
6 CitationsSource
#1Akinori OkahataH-Index: 4
#2Hiromu ItoH-Index: 51
Last. Shuichi MatsudaH-Index: 64
view all 16 authors...
OBJECTIVE: The aim of this longitudinal study was to examine the clinical significance of soluble lectin-like oxidized low-density lipoprotein receptor 1 (sLOX-1) in patients with rheumatoid arthritis. METHODS: We collected demographic and clinical data for a large rheumatoid arthritis cohort at 3 time points. Blood samples were collected at each time point; the number of samples was 282 cases in 2012, 431 cases in 2013, and 500 cases in 2014. Plasma sLOX-1 was measured by enzyme-linked immunoso...
#1S. Kondo-Ishikawa (Kyoto University)H-Index: 2
#2Takao Fujii (Kyoto University)H-Index: 32
Last. Tsuneyo Mimori (Kyoto University)H-Index: 77
view all 10 authors...
BackgroundAutoantibodies (auto Abs) and inflammatory mediators (IMs) in cerebrospinal fluid (CSF) may be involved in the pathogenesis of neuropsychiatric systemic lupus erythematosus (NPSLE). It is...
1 CitationsSource
#1Hideaki Tsuji (Kyoto University)H-Index: 8
#2Motomu Hashimoto (Kyoto University)H-Index: 21
Last. Tsuneyo Mimori (Kyoto University)H-Index: 77
view all 9 authors...
AbstractObjectives: To determine the clinical characteristics of rheumatoid arthritis (RA) patients with low serum triiodothyronine (T3) levels.Methods: We evaluated serum free T3 (fT3), free T4, a...
2 CitationsSource
#1Toshiki NakajimaH-Index: 8
#2Hajime Yoshifuji (Kyoto University)H-Index: 23
Last. Chikashi Terao (University of Shizuoka)H-Index: 8
view all 7 authors...
Background: Relapsing polychondritis (RP) is a rare inflammatory disease, which is characterized by recurrent inflammation and destruction of cartilage tissues. RP also has the profile of autoimmune disease and is often complicated with other autoimmune disease. Autoimmune thyroid disease (AITD) is one of common autoimmune diseases, which consists of Graves’ disease (GD) and Hashimoto’s thyroiditis (HT). While RP is reported to be complicated with AITD1), there has been no study on detailed prof...