Biocompatible lutein-polymer-lipid nanocapsules: Acute and subacute toxicity and bioavailability in mice
Abstract
Lutein-poly-(lactic-co-glycolic acid) (PLGA)-phospholipid (PL) nanocapsules were prepared (henceforth referred as lutein nanocapsules) and studied for acute, subacute oral toxicity and bioavailability of lutein in mice. Prior to examining the safety of lutein nanocapsules, particle size, zeta potential, surface morphology and interaction between lutein, PLGA and PL were studied. In acute study, mice were gavaged with a single dose of lutein...
Paper Details
Title
Biocompatible lutein-polymer-lipid nanocapsules: Acute and subacute toxicity and bioavailability in mice
Published Date
Dec 1, 2016
Volume
69
Pages
1318 - 1327
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