Achalasia: A New Clinically Relevant Classification by High-Resolution Manometry

Although the diagnosis of achalasia hinges on demonstrating impaired esophagogastric junction (EGJ) relaxation and aperistalsis, 3 distinct patterns of aperistalsis are discernable with high-resolution manometry (HRM). This study aimed to compare the clinical characteristics and treatment response of these 3 subtypes.One thousand clinical HRM studies were reviewed, and 213 patients with impaired EGJ relaxation were identified. These were...