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#1Mericien Venzon (NYU: New York University)H-Index: 2
#2Ken Cadwell (NYU: New York University)H-Index: 42
#1Swati G. Patel (UCB: University of Colorado Boulder)H-Index: 13
#2Folasade P. May (UCLA: University of California, Los Angeles)H-Index: 16
Last. Douglas J. Robertson (Dartmouth College)H-Index: 49
view all 9 authors...
This document is a focused update to the 2017 colorectal cancer (CRC) screening recommendations from the U.S. Multi-Society Task Force on Colorectal Cancer, which represents the American College of Gastroenterology, the American Gastroenterological Association, and the American Society for Gastrointestinal Endoscopy. This update is restricted to addressing the age to start and stop CRC screening in average-risk individuals and the recommended screening modalities. Although there is no literature...
#1Sultan Mahmood (UB: University at Buffalo, State University of New York)H-Index: 1
#2Steven Bollipo (JHH: John Hunter Hospital)H-Index: 8
Last. Jarad Martin (UoN: University of Newcastle Australia)H-Index: 27
view all 3 authors...
#1Antonio Fabio Di Narzo (MSSM: Icahn School of Medicine at Mount Sinai)H-Index: 22
#2Sander M. Houten (MSSM: Icahn School of Medicine at Mount Sinai)H-Index: 62
Last. Carmen Argmann (MSSM: Icahn School of Medicine at Mount Sinai)H-Index: 35
view all 29 authors...
Abstract null Background null Polygenic and environmental factors are underlying causes of inflammatory bowel disease (IBD). We hypothesized that integration of the genetic loci controlling a metabolite's abundance, with known IBD genetic susceptibility loci, may help resolve metabolic drivers of IBD. null Methods null We measured the levels of 1300 metabolites in the serum of 484 ulcerative colitis (UC) and 464 Crohn's disease (CD) patients and 365 controls. Differential metabolite abundance wa...
#1Chrissy Bolton (University of Oxford)H-Index: 2
#2Christopher Smillie (Broad Institute)
Last. Holm H. Uhlig (University of Oxford)H-Index: 56
view all 36 authors...
ABSTRACT: null Background and aims null Monogenic forms of inflammatory bowel disease (IBD) illustrate the essential roles of individual genes in pathways and networks safeguarding immune tolerance and gut homeostasis. null Methods null To build a taxonomy model we assessed 165 disorders. Genes were prioritized based on penetrance of IBD and disease phenotypes were integrated with multi-omics datasets. Monogenic IBD genes were classified by: (1) overlapping syndromic features; (2) response to he...
#1Alfred King-Yin Lam (Griffith University)H-Index: 61
#1Chanjuan Shi (Duke University)H-Index: 42
Last. Cian MuldoonH-Index: 14
view all 3 authors...
Endoscopic resection (ER) of the esophageal lesion is the standard of care as first line therapy for pre-invasive (dysplasia) and superficial esophageal carcinomas. Pathological examination of the ER specimen is important as it provides data which informs the likelihood of recurrence and prognosis of patients.1 null There is no internationally accepted standardized dataset for reporting pathological parameters of early esophageal neoplasia and taking account of both squamous neoplasia and Barret...
#1Claire A Beveridge (Cleveland Clinic)
#2Scott Gabbard (Cleveland Clinic)H-Index: 11
Last. Florian Rieder (Cleveland Clinic)H-Index: 44
view all 3 authors...
#1Brian Z. Huang (USC: University of Southern California)
#2Veronica Wendy Setiawan (USC: University of Southern California)H-Index: 36
#1Benoit Chassaing (University of Paris)H-Index: 3
#2Charlene Compher (University of Pennsylvania)H-Index: 46
Last. James D. Lewis (University of Pennsylvania)H-Index: 108
view all 21 authors...
Abstract null Background & Aims null Epidemiologic and murine studies suggest that dietary emulsifiers promote development of diseases associated with microbiota dysbiosis. While the detrimental impact of these compounds on the intestinal microbiota and intestinal health have been demonstrated in animal and in vitro models, impact of these food additives in healthy humans remains poorly characterized. null Methods null To examine this notion in humans, we performed a double-blind controlled-feed...
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