Original paper
Treatment of established left ventricular hypertrophy with fibroblast growth factor receptor blockade in an animal model of CKD
Volume: 29, Issue: 11, Pages: 2028 - 2035
Published: May 29, 2014
Abstract
Activation of fibroblast growth factor receptor (FGFR)-dependent signalling by FGF23 may contribute to the complex pathogenesis of left ventricular hypertrophy (LVH) in chronic kidney disease (CKD). Pan FGFR blockade by PD173074 prevented development of LVH in the 5/6 nephrectomy rat model of CKD, but its ability to treat and reverse established LVH is unknown. CKD was induced in rats by 5/6 nephrectomy. Two weeks later, rats began treatment...
Paper Details
Title
Treatment of established left ventricular hypertrophy with fibroblast growth factor receptor blockade in an animal model of CKD
Published Date
May 29, 2014
Volume
29
Issue
11
Pages
2028 - 2035
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History