Stefan Reuter
University of Münster
Internal medicineUrologyEndocrinologySurgeryPathologyRenal functionCardiologyImmunologyPositron emission tomographyKidney diseaseDiseaseEchinococcus multilocularisKidneyKidney transplantationTacrolimusTransplantationMedicineCohortBiologyGastroenterologyPharmacology
Publications 161
#1Joachim Bautz (WWU: University of Münster)H-Index: 4
#2Jörg StypmannH-Index: 45
Last. Michael Schäfers (WWU: University of Münster)H-Index: 67
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Background null We aimed to compare the prognostic value of myocardial perfusion scintigraphy (MPS) and dobutamine stress echocardiography (DSE) in patients with end-stage renal disease (ESRD) without known coronary artery disease. null Methods null Two-hundred twenty-nine ESRD patients who applied for kidney transplantation at our centre were prospectively evaluated by MPS and DSE. The primary endpoint was a composite of myocardial infarction (MI) or all-cause mortality. The secondary endpoint ...
#1Gerold ThölkingH-Index: 14
Last. Dirk Kuypers (Katholieke Universiteit Leuven)H-Index: 81
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Fast metabolism of immediate-release tacrolimus (IR-Tac) is associated with decreased kidney function after renal transplantation (RTx) compared to slow metabolizers. We hypothesized, by analogy, that fast metabolism of extended-release tacrolimus (ER-Tac) is associated with worse renal function. We analyzed data from patients who underwent RTx at three different transplant centers between 2007 and 2016 and received an initial immunosuppressive regimen with ER-Tac, mycophenolate, and a corticost...
Fast tacrolimus (Tac) metabolism is associated with reduced survival rates after renal transplantation (RTx), mainly due to cardiovascular events. Because dyslipidemia is a leading cause of cardiovascular death, we hypothesized that most RTx patients do not achieve recommended target low-density lipoprotein cholesterol (LDL-C) levels (European cardiology society guidelines) and that fast Tac metabolizers have higher dyslipidemia rates. This study included RTx recipients who received initial immu...
#1Konrad BuscherH-Index: 16
#2Barbara Heitplatz (WWU: University of Münster)H-Index: 8
Last. Stefan ReuterH-Index: 29
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BACKGROUND In transplant medicine, clinical decision-making largely relies on histology of biopsies. However, histology suffers from low specificity, sensitivity, and reproducibility, leading to suboptimal stratification of patients. We developed a histology-independent immune framework of kidney graft homeostasis and rejection. METHODS Tailored RNA deconvolution for leukocyte enumeration and co-regulated gene network analysis was applied to published bulk human kidney transplant RNA transcripto...
#1Felix BeckerH-Index: 13
Last. Ralf BahdeH-Index: 12
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Organ scarcity demands critical decision-making regarding eligible transplant candidates and graft allocation to ensure best benefit from renal transplantation (RTx). Among the controversial relative contraindications is a history of pretransplant malignancy (PTM). While oncological outcomes of PTM-RTx recipients are well described, data on graft-specific outcome are scarce. A retrospective double case control matched pair analysis (60 months follow-up) was carried out and RTx-recipients were st...
#1Ulrich JehnH-Index: 4
Last. Stefan ReuterH-Index: 29
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The prognostic significance of suPAR in various kidney diseases has recently been demonstrated. Its role in transplantation-specific outcomes is still largely unknown. Therefore, we prospectively investigated the prognostic relevance of suPAR in patients before and one year after kidney transplantation (KTx). We included 100 patients who had received a kidney transplantation between 2013 and 2015. The plasma concentration of suPAR was measured by ELISA assay. In recipients of living donations (L...
#2Tina Schmidt (Saarland University)H-Index: 15
Last. Barbara SuwelackH-Index: 21
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The management of multidrug-resistant strains of cytomegalovirus after solid organ transplantation is challenging. This case report demonstrates the successful treatment of a multidrug-resistant strain of cytomegalovirus that may represent a valuable option for problematic cases. This report illustrates the emergence of a multidrug-resistant cytomegalovirus (CMV) UL54 mutant strain in a renal transplant recipient with severe lymphopenia and thrombocytopenia. We show that the combined treatment w...
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