Review paper
The Notch ligand Jagged1 as a target for anti-tumor therapy
Abstract
The Notch pathway is increasingly attracting attention as a source of therapeutic targets for cancer. Ligand-induced Notch signaling has been implicated in various aspects of cancer biology; as a consequence, pan-Notch inhibitors and therapeutic antibodies targeting one or more of the Notch receptors have been investigated for cancer therapy. Alternatively, Notch ligands provide attractive options for therapy in cancer treatment due to their...
Paper Details
Title
The Notch ligand Jagged1 as a target for anti-tumor therapy
Published Date
Jan 1, 2014
Journal
Volume
4
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Notes
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